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Clinical use of a haemoglobin-based oxygen-carrying solution in dogs and cats

HAEMOGLOBIN-based oxygen-carrying (HBOC) solutions have been extensively developed and studied in the human medical field over the past three decades as a means of providing a readily available alternative to red blood cell (RBC) transfusion, due to increased concerns over disease transmission and limited supplies of human blood. Their use so far in human clinical medicine has been restricted by the lack of licensed products. Recently, an HBOC solution for the treatment of anaemia in dogs (Oxyglobin; Biopure) has been licensed in the UK. This article, based on the authors' experience of using the product to date, discusses the clinical applications, and limitations, of this new addition to the veterinary clinician's armoury.

Sophie Adamantos graduated from Liverpool in 1999 and is currently a third year clinical training scholar in emergency and critical care at the Royal Veterinary College (RVC).

Amanda Boag graduated from Cambridge in 1998. She is a lecturer in emergency and critical care/internal medicine at the RVC.

Dez Hughes graduated from Liverpool in 1990. He is a senior lecturer at the RVC and director of its emergency and critical care service.